What Is TB-500?
Thymosin beta-4 is a naturally occurring protein involved in how cells move and organize, especially where tissue is under repair. TB-500 is a synthetic peptide modeled on the active region of that protein. The form prescribed at Evolve Health is TB-500 acetate.
What Researchers Are Studying
Research on TB-500 is still early and comes mostly from laboratory and animal work. Areas of interest include:
- Supporting the body's natural tissue-recovery processes after strain or training
- Flexibility and mobility
- Recovery and return to activity as part of a broader plan
Active adults, weekend athletes, people who train hard, and anyone frustrated by slow recovery, are the patients who ask us about TB-500 most often.
How It's Prescribed at Evolve Health
TB-500 acetate is prescribed as a subcutaneous or intramuscular injection. It is always prescribed as a single-ingredient formulation and is never combined with another peptide.
Prescriptions are written for one patient and filled by a LegitScript-certified 503A compounding pharmacy using ingredients from FDA-registered facilities with a certificate of analysis.
Is TB-500 Right for You?
Your provider decides that with you during a comprehensive consultation that covers your health history, medications, activity level, goals, and labs. TB-500 may not be appropriate during pregnancy or breastfeeding, or with an active cancer or one under evaluation.
What to Expect
After your consultation and labs, your provider builds a plan, shows you how to administer your medication, and schedules an early check-in. Follow-up visits track how you're feeling and whether the plan should change.
Disclaimer: Compounded peptides are not FDA-approved for the diagnosis, treatment, cure, or prevention of any disease. The FDA does not evaluate or verify the safety, effectiveness, or quality of compounded drugs. These peptides may be prescribed in certain cases based on individual clinical judgment following a patient-specific evaluation, and prescriptions are fulfilled exclusively by a LegitScript-certified 503A compounding pharmacy pursuant to a patient-specific prescription. Results vary. Information current as of November 2026.





